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Category:Danish brandsCongenital myopathies.
There are several congenital myopathies that are genetically defined and have an obvious biochemical defect, such as the myofibrillar myopathies, the glycosylation disorders, the hypomyelination myopathies, the alpha-dystroglycanopathies, the congenital distal arthrogryposis syndromes, and the merosin-deficient congenital muscular dystrophies. There are also many genetically uncharacterized myopathies with a wide range of clinical and biochemically defined phenotypes, which do not fit into any specific clinicopathological classification. The reason for this lies in the fact that many of the diseases that belong to this group are not recessive, that is, they are associated with only one pathogenic gene mutation and that the majority of cases are not transmitted through an autosomal recessive mode of inheritance. However, most cases are due to a complex genetic situation with a large number of interacting genes. In this review we will discuss the progress in the knowledge of the genetic basis of the uncharacterized myopathies and present a clinically and biochemically based approach to their diagnosis.The anti-proliferative effects of relaxin on the uterus and endometrium of the pregnant rabbit.
The effect of relaxin was studied in vitro and in vivo be359ba680
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